Table 1 Cohort description including age (years), symptoms/presentation in clinic, site of manifestation, and severity according to rASRM/Enzian classification for each of the 26 patients enrolled in the study

1/FA

47

Tumor left ovary (12cm)

Endometriosis of the left adnexa or parametria, Adenomyosis uteri interna

ASRM III FA

2/FA

52

Bleeding disorder

Adenomyosis uteri interna

0/FA

3/FA

38

Symptomatic uterus myomatosus

Adenomyosis uteri interna

0/FA

4/FA

36

Dysmenorrhea

Adenomyosis uteri interna

0/FA

5/FA

65

Recurrent postmenopausal bleeding

Adenomyosis uteri interna

0/FA

6/FA

45

Bleeding disorder

Adenomyosis uteri interna

0/FA

7/FA

56

Bleeding disorder

Adenomyosis uteri interna

0/FA

1/DIE

33

Endoscopic findings suspicious for endometriosis in the proximal rectum

Partial sigmoid resectate with a florid, deeply infiltrating endometriosis

ASRM IV ENZIAN C3

2/DIE

46

Large endometrioma in the rectovaginal septum with vaginal pole and intestinal infiltration

(1) Endometriosis lesions in the area of the PE from the sigmoid wall (2) Extensive endometrioma in the rectal area with transition into the vaginal wall

ENZIAN A3C3

3/DIE

43

Dysmenorrhea

Partial resection of the urinary bladder with extensive tumor-like endometriosis

ENZIAN FB

4/DIE

28

Dysmenorrhea

Endometriosis lesions of the urinary bladder wall, colon wall and in the smooth muscular soft tissue

ASRM III

ENZIAN A3 C3 FB

5/DIE

45

Subileus

Terminal ileum resectate with endometriosis

FI

6/DIE

44

Size-progressive mass in the area of the sigmoid colon

Partial sigmoid resection with central endometriosis

ASRM II ENZIAN C3 FO

7/DIE

30

Symptomatic endometriosis with vaginal and rectal involvement

Rectum resectate including vagina part with extensive endometriosis lesions

ASRM IV ENZIAN A3C3

8/DIE

41

Symptomatic endometriosis

Rectosigmoid with numerous, deeply infiltrating endometriosis lesions intramurally.

ASRM II ENZIAN A2C2

9/DIE

25

Deeply infiltrated endometriosis in the area of the posterior vaginal wall as well as Douglas’ space

Partial colon resection with infiltrating endometriosis.

ASRM II ENZIAN A2 C2 FO

10/ DIE

32

Deep infiltrating endometriosis of Douglas, pelvic peritoneum, bladder wall, vagina, and subphrenic on right side

(1) Vaginal wall with multiple and partially hemorrhaged, deeply infiltrating endometriosis lesions (2) Bladder wall with deeply infiltrating endometriosis

ASRM II ENZIAN A2 FB Fo

11/DIE

30

Recurrent perianal bleeding during menstruation.

Rectal resectate with multifocal manifestations of endometriosis located in the muscular wall as well as in the mesorectal adipose tissue.

ASRM II ENZIAN A1-2C2

12/DIE

36

Extensive intraperitoneal and pelvic endometriosis

1.Partial colon resectate (C. sigmoideum) with numerous endometriosis lesions 2. Ileocecal resectate with additional endometriosis lesions in the wall.

ASRM IV ENZIAN C2-3 FB FI

13/DIE

19

Dysmenorrhea

Partial colon resection with an invasive endometriosis with infiltration of the muscularis propria

ASRM II ENZIAN A2 C2 FB

14/DIE

23

Deep infiltrating Douglas endometriosis with involvement of the vagina

Douglas PE with marked, apparently deep infiltrating endometriosis.

ASRM (negative)

ENZIAN A2-3 C2-3

15/DIE

34

Dysmenorrhea

Tumor-like endometriosis in the PE from the septum rectumvaginale with vaginal pole

ASRM IV ENZIAN B2-3 C2 FB

16/DIE

31

Monthly hematochezia

Resectate of the sigmoid colon with multiple endometriosis lesions of the entire intestinal wall with continuity to the intestinal lumen and serosa.

ASRM IV ENZIAN A3C3 FI

17/DIE

34

Deeply infiltrated endometriosis

Rectosigmoid resectate with extended endometriosis lesions

ASRM IV ENZIAN A3 C3

18/DIE

29

Dysmenorrhea

Recto-vaginally manifested, spreading to the rectum to the submucosa and to the vaginal wall

ASRM IV ENZIAN A3 C3

19/DIE

31 J

Known deeply infiltrated endometriosis

Infiltrating endometriosis (vaginal).

ASRM III ENZIAN A3