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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Comparing gene expression in deep infiltrating endometriosis with adenomyosis uteri: evidence for dysregulation of oncogene pathways

Fig. 4

(a) KEGG enrichment analyses for differentially upregulated genes (p < 0.05, n = 116), 12 most significantly upregulated pathways are shown. This analysis revealed upregulating of signaling pathways in DIE, most significantly the PI3K pathway, but also pathways involved in virus infection, focal adhesion, endocrine resistance and malignancy. (b) Same KEGG analysis, for differentially downregulated genes (p < 0.05, n = 46), 4 most significant pathways (p < 0.0001) are shown. Here, RAS, PI3K-AKT, RAP1 and Calcium signaling pathways are significant

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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