Fig. 5

Predictive value of LASSO genes for NOA. A The relationship between binomial deviance showed the optimal Lamba parameter. B The relationship between LASSO coefficients and turning parameter, each curve denotes a coefficient. C The ROC curves of the LASSO model in the training group, testing group, and validation set. D The seven LASSO genes with AUCs > 0.8 in the GSE9210 and GSE145467 datasets. E The AUCs were shown in the testing group and validation set for the seven key genes, including REC8, CPS1, DHX57, RRS1, GSTA4, SI, and COX7B. NOA: non-obstructive azoospermia; LASSO: Least absolute shrinkage and selection operator; ROC: receiver operating characteristic; AUC: area under the curve