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Table 1 GO enrichment analysis of DEGs from uterine fluid samples

From: Can biomarkers identified from the uterine fluid transcriptome be used to establish a noninvasive endometrial receptivity prediction tool? A proof-of-concept study

Category

Term

Gene count

p-value

Fold Enrichment

FDR

Biological Process

GO:0007165 ~ signal transduction

83

2.92E-05

1.59

0.05

GO:0045944 ~ positive regulation of transcription from RNA polymerase II promoter

60

1.40E-02

1.36

22.49

GO:0000122 ~ negative regulation of transcription from RNA polymerase II promoter

50

2.60E-03

1.54

4.61

GO:0045893 ~ positive regulation of transcription, DNA-templated

39

1.98E-03

1.68

3.53

GO:0006357 ~ regulation of transcription from RNA polymerase II promoter

36

8.56E-04

1.81

1.54

GO:0006954 ~ inflammatory response

26

3.67E-02

1.52

49.24

GO:0043065 ~ positive regulation of apoptotic process

24

9.19E-03

1.77

15.42

GO:0050900 ~ leukocyte migration

21

5.05E-07

3.82

0.00

GO:0001525 ~ angiogenesis

21

2.68E-03

2.09

4.75

GO:0008360 ~ regulation of cell shape

18

1.87E-04

2.85

0.34

Cellular Component

GO:0005737 ~ cytoplasm

298

7.41E-08

1.30

0.00

GO:0005634 ~ nucleus

270

8.01E-03

1.13

10.94

GO:0005829 ~ cytosol

200

8.78E-07

1.37

0.00

GO:0070062 ~ extracellular exosome

183

1.55E-08

1.48

0.00

GO:0005654 ~ nucleoplasm

157

5.89E-04

1.28

0.85

GO:0016020 ~ membrane

146

2.40E-07

1.51

0.00

GO:0005739 ~ mitochondrion

81

2.41E-03

1.38

3.42

GO:0005615 ~ extracellular space

75

2.61E-02

1.27

31.66

GO:0048471 ~ perinuclear region of cytoplasm

38

3.75E-02

1.39

42.34

GO:0009986 ~ cell surface

34

3.70E-02

1.43

41.92

Molecular Function

GO:0005515 ~ protein binding

492

2.66E-12

1.23

0.00

GO:0044822 ~ poly(A) RNA binding

72

3.03E-03

1.41

4.64

GO:0008270 ~ zinc ion binding

66

4.84E-02

1.24

54.05

GO:0042803 ~ protein homodimerization activity

46

2.32E-02

1.39

30.79

GO:0043565 ~ sequence-specific DNA binding

33

4.91E-02

1.40

54.63

GO:0003682 ~ chromatin binding

32

1.88E-03

1.80

2.90

GO:0005102 ~ receptor binding

27

1.07E-02

1.69

15.49

GO:0003779 ~ actin binding

26

9.10E-04

2.06

1.42

GO:0008134 ~ transcription factor binding

26

1.23E-03

2.02

1.90

GO:0044212 ~ transcription regulatory region DNA binding

17

3.33E-02

1.76

41.17