From: Post-warming culture of human vitrified blastocysts with prolactin improves trophoblast outgrowth
Control | Prolactin | P value | |
---|---|---|---|
No. of donated samples, n | 166 | 208 | |
Donor age (year) | 37.2 ± 3.7 | 36.9 ± 3.6 | 0.4942 |
Insemination method | |||
Conventional in vitro fertilization, n (%) | 60 (36.1) | 73 (35.1) | 0.8333 |
Intracytoplasmic sperm injection, n (%) | 106 (63.9) | 44 (64.9) | |
Culture time to the expanded blastocyst stage (h) | 129.9 ± 11.4 | 129.7 ± 11.3 | 0.8380 |
No. of Day 5 blastocysts, n (%) | 77 (46.4) | 89 (53.6) | 0.6760 |
No. of Day 6 blastocysts, n (%) | 101 (48.6) | 107 (51.4) | |
Blastocyst diameter (μm) | 181.8 ± 20.1 | 183.6 ± 20.0 | 0.3578 |
Morphological grade (Gardner’s criteria) | |||
Inner cell mass | |||
Grade A | 26 (15.7) | 35 (16.8) | 0.6920 |
Grade B | 56 (33.7) | 77 (37.0) | |
Grade C | 84 (50.6) | 96 (46.2) | |
Trophectoderm | |||
Grade A | 23 (13.9) | 24 (11.5) | 0.3385 |
Grade B | 40 (24.1) | 64 (30.8) | |
Grade C | 103 (62.1) | 120 (57.7) |