Table 4 Effects of sperm ROS on in vitro embryo development in patients with different types of ovulation disorders (multiple logistic regression analysis)
Ovulation disorders Group | n | 2PN rate | Day 3 embryo development rate | Day 3 embryo utilization rate | Good-quality day 3 embryo rate | Blastocyst utilization rate | Good-quality blastocyst rate | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | |||
PCOS | 50 | log-mROS | 0.959 (0.792–1.793) | 0.101 | 1.379 (0.990–1.931) | 0.059 | 1.044 (0.770–1.413) | 0.782 | 1.435 (1.045–1.981) | 0.026 | 1.026 (0.682–1.546) | 0.902 | 1.125 (0.748–1.700) | 0.572 |
log-hydrogen peroxide | 1.275 (0.815–2.003) | 0.288 | 0.615 (0.434–0.864) | 0.006 | 1.101 (0.783–1.547) | 0.580 | 0.787 (0.557–1.106) | 0.170 | 0.555 (0.353–0.864) | 0.009 | 0.461 (0.292–0.718) | 0.001 | ||
Abnormal ovulation without PCOS | 40 | log-mROS | 1.351 (1.257–1.931) | 0.042 | 1.192 (0.836–1.699) | 0.331 | 1.985 (1.435–2.777) | <.0001 | 1.713 (1.106–2.707) | 0.018 | 0.673 (0.402–1.105) | 0.123 | 1.132 (0.707–.0825) | 0.607 |
log-hydrogen peroxide | 0.558 (0.315–1.242) | 0.072 | 1.263 (0.845–1.916) | 0.261 | 1.526 (0.897–2.628) | 0.122 | 1.408 (0.853–2.355) | 0.184 | 1.500 (0.893–2.529) | 0.124 | 0.883 (0.423–1.846) | 0.740 | ||