Table 1 Comparison between the anovulatory group and the normo-ovulatory group

No. of IVF cycles (n)

90

Female age (y)

30.4 ± 3.7

31.2 ± 4.4

0.086^b

1.051(0.993–1.112)

Female BMI (kg/m²)

22.6 ± 3.9

22.2 ± 3.0

0.388 ^b

0.969(0.901–1.041)

 Primary

52

139

 Secondary

38

Starting dose of Gn(U)

197.0 ± 48.0

227.2 ± 52.0

< 0.0001 ^b

1.012(1.007–1.017)

Days of stimulation

10.1 ± 1.8

10.9 ± 1.9

< 0.0001 ^b

1.292(1.120–1.490)

Total dose of Gn(U)

2036.6 ± 790.2

2602.1 ± 785.3

< 0.0001 ^b

1.001(1.001–1.001)

b-FSH (mIU/ml)

7.1 ± 2.4

8.0 ± 2.1

0.002 ^b

1.206(1.068–1.362)

b-LH (mIU/ml)

7.5 ± 4.5

4.6 ± 2.7

< 0.0001 ^b

0.771(0.706–0.843)

b-FSH/bLH

1.3 ± 1.5

2.1 ± 1.4

< 0.0001 ^b

3.019(2.021–4.511)

AFC (n)

20.2 ± 9.5

13.8 ± 6.6

< 0.0001 ^b

0.894(0.861–0.929)

AMH (ng/ml)

7.4 ± 4.1

3.8 ± 2.2

< 0.0001 ^b

0.653(0.588–0.727)

No. of oocytes retrieved

17.1 ± 7.1

13.8 ± 7.4

< 0.0001 ^b

0.943(0.914–0.973)

Male age (y)

33.1 ± 5.3

33.9 ± 5.5

0.248 ^b

1.207(0.982–1.075)

Sperm concentration (10⁶/ml)

94.2 ± 63.7

96.6 ± 66.3

0.760 ^b

1.001(0.997–1.004)

Semen round cells (10⁶/ml)

0.59 ± 1.8

0.52 ± 0.7

0.739 ^b

0.968(0.800–1.172)

Progressive motility (%)

58.6 ± 15.3

56.7 ± 15.1

0.306 ^b

0.992(0.976–1.008)

Normal morphology (%)

7.8 ± 6.6

7.1 ± 3.9

0.216 ^b

0.971(0.926–1.018)

Sperm mitochondrial ROS rate (%)

3.3 ± 2.4

3.4 ± 2.5

0.789 ^b

1.013(0.921–1.114)

Sperm hydrogen peroxide rate (%)

0.5 ± 0.4

0.5 ± 0.5

0.420 ^b

1.242(0.734–2.103)

Fertilization rate (%)

88.2 ± 15.9

89.0 ± 14.6

0.644 ^b

1.433(0.311–6.597)

2PN rate (%)

68.9 ± 21.1

73.3 ± 18.4

0.055 ^b

3.212(0.973–10.602)

≥3PN rate (%)

9.2 ± 10.7

9.2 ± 11.5

0.968 ^b

0.958(0.120–8.657)

Cleavage rate (%)

96.6 ± 19.9

97.4 ± 18.9

0.669 ^b

1.352(0.340–5.375)

Day 2 Embryo development rate (%)

57.7 ± 27.9

56.3 ± 25.7

0.655 ^b

0.812(0.326–2.023)

Day 3 Embryo development rate (%)

38.8 ± 25.7

40.5 ± 26.5

0.605 ^b

1.271(0.512–3.154)

Day 3 Embryo utilization rate (%)

58.3 ± 19.5

61.6 ± 20.5

0.179 ^b

2.205(.697–6.980)

Good-quality day 3 embryo rate (%)

30.5 ± 20.5

33.7 ± 21.1

0.204 ^b

2.115(0.666–6.717)

D5 Blastocyst utilization rate (%)

33.9 ± 26.7

30.7 ± 25.9

0.091 ^b

0.223(0.089–0.557)

D5 Good-quality blastocysts rate (%)

29.6 ± 24.5

27.7 ± 24.0

0.105 ^b

0.247(0.092–0.662)

D6 Blastocyst utilization rate (%)

28.2 ± 20.3

30.7 ± 27.8

0.473 ^b

1.434(0.535–3.844)

D6 Good-quality blastocysts rate (%)

21.6 ± 18.1

22.4 ± 24.9

0.788 ^b

1.161(0.391–3.449)

Blastocyst development rate (%)

66.8 ± 25.0

63.1 ± 32.0

0.352 ^b

0.668(0.286–1.562)

Blastocyst utilization rate (%)

59.4 ± 23.4

53.4 ± 31.5

0.125 ^b

0.508(0.214–1.206)

Good-quality blastocyst rate (%)

51.2 ± 24.2

46.2 ± 29.7

0.080 ^b

0.374(0.154–0.911)