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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: MiR-145 is upregulated in the retarded preimplantation embryos and modulates cholesterol levels in mice preimplantation embryos through targeting Abca1

Fig. 2

miR-145 suppresses murine embryogenesis. Morphological (A) and quantitative (B) analyses of the 2-cell, 4-cell, 8-cell, and blastocyst stages of murine oocyte advancement following miR-145 mimic (n = 126) or negative control (Control) (n = 102) microinjection into oocytes, with untreated control samples (Normal) (n = 189) being analyzed in parallel. The images were taken at 16 h (2-cell), 40 h (4-cell), 52 h (8-cell), and 74 h (blastocyst) after transfer of the zygotes to KSOM. The assessments have been repeated five times. ANOVA test, **P < 0.01; ****P < 0.0001. NS, no significance

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