Pregnancy outcomes | No pregnancy | Ectopic pregnancy | Intrauterine pregnancy | Heterotopic pregnancy | P valuea | P valueb |
---|---|---|---|---|---|---|
Number of cases | N = 8144 | N = 182 | N = 5378 | N = 14 | ||
Female age ya | 33.4 (5.1) | 31.8 (3.8) | 31.7 (4.1) | 31.8 (4.7) | < 0.001 | 0.93 |
Male age ya | 34.8 (6.1) | 32.5 (4.5) | 33.1 (5.2) | 35.1 (5.8) | < 0.001 | 0.09 |
BMI kg/m2a | 23.0 (3.6) | 23.1 (3.8) | 22.7 (3.5) | 23.7 (3.0) | < 0.001 | 0.09 |
Infertile age ya | 3.0 (2.0-5.0) | 3.0 (2.0-4.0) | 3.0 (1.0-4.0) | 3.5 (2.0-5.0) | < 0.001 | 0.99 |
Ectopic history | 596 (7%) | 26 (14%) | 477 (9%) | 3 (21%) | < 0.001 | 0.01 |
Reason for IVF | ||||||
Ovulatory dysfunction | 898 (11%) | 33 (18%) | 520 (10%) | 1 (7%) | < 0.001 | < 0.001 |
Endometriosis | 372 (5%) | 7 (4%) | 264 (5%) | 2 (14%) | 0.26 | 0.51 |
Tubal | 5054 (62%) | 98 (54%) | 3232 (60%) | 6 (43%) | 0.01 | 0.09 |
Male | 3989 (49%) | 78 (43%) | 2766 (51%) | 7 (50%) | 0.01 | 0.02 |
Primary infertility | 4502 (55%) | 90 (49%) | 3085 (57%) | 5 (36%) | 0.01 | 0.03 |
Parity | 771 (9%) | 10 (5%) | 389 (7%) | 1 (7%) | < 0.001 | 0.37 |
GnRH antagonist | 4947 (61%) | 127 (70%) | 2706 (50%) | 5 (36%) | < 0.001 | < 0.001 |
Gn daysa | 11.1 (2.5) | 10.9 (2.5) | 11.4 (2.5) | 12.1 (3.6) | < 0.001 | < 0.01 |
Gn doses IUa | 2921 (1209) | 2556 (1021) | 2773 (1154) | 3079 (970) | < 0.001 | 0.01 |
Sperm donor | 180 (2%) | 6 (3%) | 182 (3%) | 0 (0%) | < 0.001 | 0.95 |
EMT mma | 10.6 (1.7) | 10.1 (1.5) | 11.1 (1.6) | 10.5 (1.6) | < 0.001 | < 0.001 |
Thin endometrium | 211 (3)% | 7 (4%) | 47 (1%) | 0 (0%) | < 0.001 | < 0.001 |
Oocyte yield a | 9 (5) | 11 (4) | 11 (5) | 10 (4) | < 0.001 | 0.89 |
Estradiol levela | 5609 (3847-8418) | 6259 (4714-9602) | 6072 (4214-9170) | 5521 (3487-9012) | < 0.001 | 0.24 |
ICSI | 2619 (32%) | 42 (23%) | 1772 (33%) | 5 (36%) | 0.04 | < 0.01 |
Blastocyst transfer | 508 (6%) | 8 (4%) | 236 (4%) | 0 (0%) | < 0.001 | 1.00 |
Single embryo transfer | 1532 (19%) | 19 (10%) | 534 (10%) | 0 (0%) | < 0.001 | 0.82 |
At least one poor-quality embryo transferred | 401 (5%) | 1 (1%) | 140 (3%) | 1 (7%) | < 0.001 | 0.08 |