Table 1 Association between the levels of hsa-miR-320-3p and hsa-miR-483-5p in granulosa cells from human follicular fluids and reproductive outcomes of assisted reproductive technology (ART)
Parameters | P-value | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Q1 | % | Q2 | % | Q3 | % | Q4 | % | ||
hsa-miR-320a-3p | |||||||||
Normal fertilization rate | |||||||||
IVF cycles | 201/358 | 56.1 | 201/361 | 55.7 | 203/405 | 50.1 | 225/368 | 61.1 | < 0.05 |
ICSI cycles | 95/131 | 72.5 | 74/96 | 77.1 | 93/142 | 65.5 | 37/61 | 60.7 | NS |
Good-quality embryo rate | 212/296 | 71.6 | 205/275 | 74.5 | 214/296 | 72.3 | 149/262 | 56.9 | < 0.0001 |
Blastulation rate | 81/212 | 38.2 | 65/205 | 31.7 | 82/214 | 38.3 | 55/149 | 36.9 | NS |
hsa-miR-483-5p | |||||||||
Normal fertilization rate | |||||||||
IVF cycles | 167/341 | 49.0 | 258/457 | 56.5 | 173/346 | 50.0 | 232/348 | 66.7 | NS |
ICSI cycles | 105/134 | 78.4 | 52/74 | 70.3 | 83/133 | 62.4 | 59/89 | 66.3 | NS |
Good-quality embryo rate | 225/272 | 82.7 | 203/310 | 65.5 | 197/256 | 77.0 | 155/291 | 53.3 | < 0.0001 |
Blastulation rate | 86/225 | 38.2 | 78/203 | 38.4 | 55/197 | 27.9 | 64/155 | 41.3 | < 0.05 |