Table 3 The pooled results for ADAMTS family members downregulation and IVF-ET Outcomes

Follicles punctured

ADAMTS-1

2

7.24 (4.61 to 9.88)

< 0.001

0.0

0.374

ADAMTS-4

1

7.20 (3.69 to 10.71)

< 0.001

-

-

ADAMTS-5

1

7.20 (3.69 to 10.71)

< 0.001

-

-

ADAMTS-9

1

6.38 (3.13 to 9.63)

< 0.001

-

-

Oocytes retrieved

ADAMTS-1

3

1.61 (1.28 to 1.93)

< 0.001

0.0

0.379

ADAMTS-4

1

3.63 (1.19 to 6.07)

0.004

-

-

ADAMTS-5

1

3.63 (1.19 to 6.07)

0.004

-

-

ADAMTS-9

1

3.20 (0.90 to 5.50)

0.006

-

-

Metaphase II oocytes

ADAMTS-1

2

1.14 (-1.74 to 4.02)

0.439

0.0

0.958

ADAMTS-4

1

1.30 (-0.64 to 3.24)

0.189

-

-

ADAMTS-5

1

1.30 (-0.64 to 3.24)

0.189

-

-

ADAMTS-9

1

1.30 (-5.47 to 8.07)

0.707

-

-

Germinal vesicle oocytes

ADAMTS-1

1

2.89 (2.64 to 3.14)

< 0.001

-

-

ADAMTS-4

1

2.19 (2.01 to 2.37)

< 0.001

-

-

ADAMTS-5

1

2.19 (2.01 to 2.37)

< 0.001

-

-

ADAMTS-9

1

2.89 (2.64 to 3.14)

< 0.001

-

-

Oocytes recovery rate

ADAMTS-1

2

0.27 (0.05 to 1.61)

0.152

40.6

0.195

ADAMTS-4

1

0.08 (0.00 to 1.47)

0.089

-

-

ADAMTS-5

1

0.08 (0.00 to 1.47)

0.089

-

-

ADAMTS-9

1

0.06 (0.00 to 1.19)

0.066

-

-

Oocyte maturity rate

ADAMTS-1

3

0.64 (0.32 to 1.29)

0.211

0.0

0.900

ADAMTS-4

1

0.63 (0.21 to 1.89)

0.405

-

-

ADAMTS-5

1

0.63 (0.21 to 1.89)

0.405

-

-

ADAMTS-9

1

0.52 (0.17 to 1.63)

0.263

-

-

Fertilization rate

ADAMTS-1

3

0.85 (0.50 to 1.45)

0.554

0.0

0.498

ADAMTS-4

1

0.63 (0.25 to 1.62)

0.340

-

-

ADAMTS-5

1

0.63 (0.25 to 1.62)

0.340

-

-

ADAMTS-9

1

0.90 (0.36 to 2.24)

0.815

-

-

Cleavage rate

ADAMTS-1

2

0.33 (0.05 to 2.15)

0.246

0.0

0.954

Good-quality embryos rate

ADAMTS-1

2

0.76 (0.41 to 1.41)

0.381

0.0

0.586

Blastocyst formation rate

ADAMTS-1

1

0.68 (0.30 to 1.57)

0.371

-

-

Clinical pregnancy rate

ADAMTS-1

1

0.90 (0.37 to 2.20)

0.820

-

-