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Table 1 Partial classification of the differentially expressed proteins

From: Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Classify

Gene

Physiological processes

Immunoregulation

Rbm14, Il1rap

innate immune response

Casp1

regulation of inflammatory response

Enpp1

immune response

Respond to stress

Casp1, Srp72, Ube2b, Jund,

respond to drug

Serpina7, Aldh3a

Hmox2, Hsp90b1, Casp1, Aldh3a1

respond to hypoxia

Eif2s1, Pdcd6

respond to heat

Hmox2, Atox1

respond to oxidative stress

Lipid metabolism

Apoc2, Apoa4, Sult1e1, Acbd7, Nr5a1, Vcp

lipid binding

Lipf, Pld3, Ces1b, Plbd1

lipid catabolic process

Arfip2, Nr5a1, Apoa4

phospholipid binding

Apoa4

positive regulation of lipid biosynthetic process; lipid homeostasis; lipid transport

Lipf, Hacl1, Echdc2, Pld3, Plbd1, Ptgds

lipid metabolic process

Vcp

lipid droplet

Endoplasmic reticulum function

Vcp, Rrbp1, Pdia3, Hsp90b1, Hsp90aa1, Eif2s1, Dnajb11

Protein processing in endoplasmic reticulum

Fertility

Ube2b

sperm axoneme assembly

Cd9

fusion of sperm to egg plasma membrane involved in single fertilization

Insl6, Acrbp

spermatid development

Acrbp

sperm capacitation

Hsp90aa1

sperm flagellum

Insl6

flagellated sperm motility

Insl6, Ube2b

spermatogenesis

Fgf2, Camsap3

embryo development ending in birth or egg hatching

Zp3r, Cct6a

binding of sperm to zona pellucida