Fig. 1From: Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice Obesity induced the oxidative stress and poor sperm quality in mouse epididymis. A The body weight of obese mice significantly increased compared to that in control mice. B-C The comparisons between normal mice and obese mice in sperm motility and concentration. D In the caput epididymis of the obese mice, the ratio of the GSH/GSSG decreased. E The concentration of MDA increased significantly in the epididymis fluid of the obese mice. F The level of ROS increased in the sperm of obese mice. All data were presented as mean ± SD, *P < 0.05, **P < 0.01, ****P < 0.0001Back to article page