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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3

Fig. 3

The expression profiles of miR-92b-3p. A A heatmap depicting the expression level of 13 miRNA in EVs from uterine flushing fluids on D10, D13 and D18. B The expression level of miR-92b-3p in porcine endometrium on D10, D13 and D18. C The conservation of miR-92b-3p from 6 different species. D The transmission of fluorescent miR-92b-3p in the transwell chamber. The EECs transfected with fluorescent miR-92b-3p were placed in the upper chamber, and the PTr2 cells were placed in the upper chamber. Scale bar = 50 μm. E After treating PTr2 cells with miR-92b-3p derived from EECs extracellular vesicles for 48 h, the expression of miR-92-3p increased significantly. Data are mean ± s.d., derived from three independent experiments. * P < 0.05, * *P < 0.01 (Student’s t-test)

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