Table 3 Hormone profile, luteal support, and pregnancy outcomes according to the two GnRH-a protocols before and after propensity score matching

E₂ value on hCG + 4 day (pg/ml)

1316.43 (569.82)

1292.35 (591.67)

0.252

1308.32 (571.99)

1277.97 (555.17)

0.267

P value on hCG + 4 day (ng/ml)

182.55 (68.12)

194.24 (71.28)

0.057

183.92 (67.74)

186.01(71.13)

0.528

E₂ value on hCG + 9 day (pg/ml)

1301.87 (1095.22)

1663.89(1184.46)

 < 0.001

1304.89(1109.56)

1699.51(1183.88)

 < 0.001

P value on hCG + 9 day (ng/ml)

78.57 (67.71)

100.40 (91.68)

 < 0.001

80.17 (69.03)

107.95 (96.44)

 < 0.001

Luteal support, n (%)

0.111

0.057

 C

133/1193 (11.15)

334/2851 (11.72)

90/964 (9.34)

108/964 (11.20)

 C + D

92/1193 (7.71)

238/2851 (8.35)

80/964 (8.30)

99/964 (10.27)

 C + D + P

703/1193 (58.93)

1741/2851 (61.07)

577/964 (59.85)

579/964 (60.06)

 C + D + P + F

265/1193 (22.21)

538/2851 (18.86)

217/964 (22.51)

178/964 (18.46)

Implantation rate (%)

47.05 (43.70)

52.49 (44.13)

 < 0.001

47.44 (43.81)

52.26 (44.60)

0.017

Biochemical pregnancy rate (%)

769/1193 (64.46)

1976/2851(69.31)

0.003

619/964 (64.21)

665/964 (68.98)

0.026

Clinical pregnancy rate (%)

696/1193 (58.34)

1802/2851 (63.21)

0.004

552/964 (57.26)

600/964 (62.24)

0.026

Ectopic pregnancy rate (%)

10/696 (1.44)

25/1802 (1.39)

0.469

9/552 (1.63)

13/600 (2.17)

0.667

No. of fetuses in pregnancy, n (%)

0.011

0.033

 Single

520/696 (74.71)

1237/1802 (68.65)

419/552 (75.91)

422/600 (70.33)

 Twins

176/696 (25.29)

565/1802 (31.35)

133/552 (24.09)

178/600 (29.67)

Early pregnancy loss rate (%)

82/696 (11.78)

209/1802 (11.60)

0.469

63/552 (11.41)

61/600 (10.17)

0.667

Mid- and late-term pregnancy loss rate (%)

23/696 (2.44)

51/1802 (2.83)

0.469

13/552 (2.36)

15/600 (2.50)

0.667

Preterm birth rate (%)

91/696 (13.07)

285/1802 (15.82)

0.093

66/552 (11.96)

87/600 (14.50)

0.214

Live birth rate (%)

581/1193 (48.70)

1517/2851 (53.21)

0.009

467/964 (48.44)

511/964 (53.01)

0.045