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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway

Fig. 2

Decreased expression of TOP2A in the endometria of patients with RIF. A Immunohistochemistry analysis of paraffin-embedded endometrial tissues. TOP2A expression in the endometria of the control women and the patients with RIF. Immunohistochemical analysis was performed using a TOP2A antibody. Original magnification left panel: × 100, scale bar = 50 μm, right panel: × 200, scale bar = 20 μm. s, stroma; ge, glandular epithelium. B, C The protein and mRNA expression of TOP2A were examined separately by Western blotting and RT-qPCR in human endometria, n = 12 in each group. Representative Western blotting results for the control group and the RIF group are shown. Mann–Whitney U test. All data are represented as the mean ± SEM. **p < 0.01, ***p < 0.001

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