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Table 2 Results of univariate analysis of time to CR in fertility-sparing treatment of AEH and early EC

From: Metabolic syndrome is an independent risk factor for time to complete remission of fertility-sparing treatment in atypical endometrial hyperplasia and early endometrial carcinoma patients

 

Time to CR

OR (95%CI)

P-value

Age (years)

-0.1 (-0.3, 0.1)

0.316

BMI (kg/m2)

0.2 (-0.0, 0.3)

0.054

HOMA-IR

0.1 (-0.1, 0.4)

0.377

FBG (mmol/L)

1.6 (0.6, 2.5)

0.020

Serum insulin (μU/mL)

0.0 (-0.0, 0.1)

0.608

HDL (mmol/L)

0.2 (-0.2, 0.5)

0.347

Triglyceride (mmol/L)

0.4 (-0.1, 0.6)

0.158

IR

0.3 (-1.2, 1.8)

0.657

DM

0.1 (-1.7, 1.9)

0.932

HBP

0.2 (-2.7, 3.0)

0.914

MetS

3.0 (1.1, 5.0)

0.003

PCOS

2.0 (0.5, 3.4)

0.009

Gestation

-0.7 (-2.3, 0.8)

0.355

Parity

-1.6 (-3.6, 0.4)

0.118

Infertility

0.1 (-1.4, 1.6)

0.885

Histological type

1.0 (-0.5, 2.5)

0.197

Metformin

-0.7 (-2.2, 0.8)

0.343

MPA250mg

0.7 (-0.8, 2.2)

0.363

MPA500mg

-0.1 (-1.9, 1.8)

0.923

MA

0.9 (-1.1, 2.9)

0.380

GnRH-a

-0.9 (-3.2, 1.3)

0.418

  1. CR Complete remission, BMI Body mass index, HOMA-IR Homeostasis model assessment of insulin resistance-insulin resistance, FBG Fasting blood glucose, HDL High-density lipoprotein, IR Insulin resistance, DM Diabetes, HBP High blood pressure, MetS Metabolic syndrome, PCOS Polycystic ovarian syndrome, MPA Oral medroxyprogesterone acetate, MA Oral megestrol acetate