Table 2 Embryologic outcomes and pregnancy outcomes of PCOS group and non-PCOS group
From: Effect of TSH on oocyte maturation of PCOS patients with normal thyroid function in IVF
Outcomes | PCOS Group (n = 595) | Non-PCOS Group (n = 2595) | t/χ2 value | P value |
|---|---|---|---|---|
Gn used dosage (IU) | 2268.67 ± 889.98 | 2564.74 ± 979.87 | 45.67 | < 0.001*** |
Gn used duration (d) | 11.57 ± 1.90 | 11.40 ± 2.46 | 2.46 | 0.116 |
FSH levels on HCG trigger day (IU/L) | 13.46 ± 4.73 | 17.28 ± 6.19 | 193.59 | < 0.001*** |
LH levels on HCG trigger day (IU/L) | 1.06 ± 0.83 | 1.35 ± 1.09 | 35.59 | < 0.001*** |
E2 levels on HCG trigger day (pg/ml) | 2737.28 ± 1193.56 | 2625.42 ± 1152.41 | 4.39 | 0.036* |
P levels on HCG trigger day (ng/ml) | 0.75 ± 0.42 | 0.80 ± 0.38 | 8.74 | 0.003** |
Endometrial thickness on HCG trigger day (mm) | 11.71 ± 2.54 | 11.64 ± 2.59 | 0.31 | 0.573 |
Number of oocytes retrieved | 11.08 ± 2.84 | 9.60 ± 2.61 | 150.26 | < 0.001*** |
Number of MII stage oocytes | 10.05 ± 2.76 | 8.89 ± 2.64 | 90.68 | < 0.001*** |
Oocyte maturation rate (%) | 90.7% (5980/6594) | 92.6% (23,082/24917) | 25.57 | < 0.001*** |
2PN fertilization rate (%) | 84.57% | 86.77% | 13.35 | < 0.001*** |
Cleavage rate (%) | 99.38% | 99.30% | 0.29 | 0.588 |
Number of useable embryos | 4.20 ± 1.319 | 3.91 ± 1.233 | 26.90 | < 0.001*** |
Number of high-quality embryos | 3.16 ± 1.66 | 2.95 ± 1.58 | 8.83 | 0.003** |
High-quality embryo rate (%) | 70.6% | 71.0% | 0.13 | 0.716 |
Clinical pregnancy rate (%) | 62.7% (373/595) | 62.7% (1628/2595) | 0 | 0.983 |
Ectopic pregnancy rate (%) | 0.8% (3/373) | 1.4% (23/1628) | 0.87 | 0.349 |
Early abortion rate (%) | 15.8% (59/373) | 13.5% (220/1628) | 1.34 | 0.247 |
Live birth rate (%) | 52.3% (311/595) | 53.3% (1388/2595) | 0.28 | 0.591 |