Characteristics | Atosiban (n = 97) | Placebo (n = 97) | P-value |
---|---|---|---|
Female age(years) | 33(30–36) | 33(30–36) | 0.166 |
Body mass index (kg/m2) | 22.0(19.9–24.6) | 21.5(19.8–23.8) | 0.205 |
Antral follicle count | 12(9–19.5) | 12(8–18) | 0.796 |
FSH/HMG dosage (IU) | 2025(1650–2700) | 2025(1650–2512) | 0.640 |
FSH/HMG duration (days) | 10(8–11) | 10(8–12) | 0.863 |
Duration of infertility (years) | 4(3–6) | 4(3–6) | 0.904 |
Types of infertility, n (%) | Â | Â | 0.774 |
 Primary infertility | 51 (52.6) | 49 (50.5) |  |
 Secondary infertility | 46 (47.4) | 48 (59.5) |  |
Causes of infertility, n (%) | Â | Â | 0.091 |
 Tubal | 49(50.5) | 51 (52.6) |  |
 Male factor | 30 (30.9) | 39 (40.2) |  |
 Unexplained | 5 (5.2) | 1 (1) |  |
 Mixed | 13 (13.4) | 6 (6.2) |  |
No. of embryos previously transferred | 5(4–6) | 4(4–6) | 0.147 |
No. of previous failed embryo transfers | 4(3–4) | 3(3–4) | 0.368 |
Stimulation protocol, n (%) | Â | Â | 0.666 |
 Long agonist | 44(45.3) | 47(48.4) |  |
 Antagonist | 53(54.6) | 50(51.5) |  |
Insemination method, n (%) | Â | Â | 0.774 |
 IVF | 45(46.4) | 47(48.5) |  |
 ICSI | 52(53.6) | 50(51.5) |  |
Estradiol on hCG day (pg/ml) | 1898(1450–2552) | 2025(1354–2658) | 0.766 |
No. of oocytes obtained | 8(6–11) | 8(5–12) | 0.803 |
No. of oocytes fertilized | 5(3–8) | 6(3–8) | 0.524 |
No. of transferrable embryos | 3(2–4) | 3(2–4) | 0.560 |
Total number of top-quality embryos | 2(0–3) | 2(1–3) | 0.081 |
Endometrial thickness (mm) | 11(9.6–12) | 11(9–12) | 0.762 |
No. of embryos transferred, n (%) | Â | Â | 1.000 |
 One | 11 (11.3) | 11 (11.3) |  |
 Two | 86 (88.7) | 86 (88.7) |  |
Frequency of endometrial peristalsis (waves/min) | 2(1.8–2.3) | 2(1.5–2.3) | 0.527 |