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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: hUCMSCs reduce theca interstitial cells apoptosis and restore ovarian function in premature ovarian insufficiency rats through regulating NR4A1-mediated mitochondrial mechanisms

Fig. 6

The JC-1 polymorimonomor fluorescent ratios and apoptosis of TICs after cisplatin and hUCMSCs treatment. A, C Representative pictures of flow cytometry for each group are present. Histograms show JC-1 polymorimonomor fluorescent ratios = Q2/Q4, with Q2 representing the control membrane potential in the form of a polymer and Q4 the green fluorescence of monomers engaged in reduced membrane potentials after the intervention. B, D Apoptosis of TICs was detected with the use of Annexin V-FITC apoptosis detection kits. Scatter diagrams of PI/Annexin V gating within the different groups are present above. Representative pictures of flow cytometry for each group are present. Statistics analysis of these data is indicated within the histograms. CDDP, cisplatin.**: P < 0.01.*: P < 0.05

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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