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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Functional reorganization of monoamine transport systems during villous trophoblast differentiation: evidence of distinct differences between primary human trophoblasts and BeWo cells

Fig. 5

Inhibition of human placental cells’ serotonin uptake by antidepressant drugs. Uptake of serotonin by PHT (A) and BeWo (B) cells in the presence of selected antidepressant drugs: paroxetine (PRX), citalopram (CIT), sertraline (SRT), venlafaxine (VFX), fluvoxamine (FLV), and fluoxetine (FXT) at physiologically achievable plasma concentrations (0.3 to 3 µM). Values shown are percentages of uptake by inhibitor-free controls (CTRL). Presented data are means ± SD (n ≥ 4), with indications of statistical significance shown as a dotted line and obtained from one-way ANOVA summary compared to CTRL: **p ≤ 0.01, ***p ≤ 0.001

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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