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Table 1 Detailed semen parameters for the patient harboring SSFA2 variant

From: A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation

Human subjects

 

Normospermic parameters

Age (years)

29

NA

Consanguinity (Yes/NO)

Yes

NA

Semen parameters

 Sperm volume (mL)

3

≥1.5

 Sperm concentration (106/mL)

60.8

≥15

 Semen pH

7.3

≥7.2

 Total sperm count (106)

182.4

≥39

 Motility sperm (%)

54.3

≥40

 Progressive motility (%)

36.8

≥32

 Vitality (%)

67

≥58

 Normal spermatozoa (%)

0

≥4

 Abnormal spermatozoa (%)

100

NA

 Abnormal flagella (%)

0

NA

 Abnormal head morphology (%)

100

NA

Sperm locomotion parameters

 Curvilinear velocity (VCL) (μm/s)

33.6

NA

 Straight-line velocity (VSL) (μm/s)

19.1

NA

 Average path velocity (VAP) (μm/s)

21.3

NA

 Mean angular displacement (MAD) (degrees)

7.93

NA

 Amplitude of lateral head displacement (ALH) (μm)

1.8

NA

 Beat-cross frequency (BCF) (Hz)

5.4

NA

 Linearity (LIN)

54.9

NA

 Wobble (WOB, = VAP/VCL)

61.9

NA

 Straightness (STR, = VSL/VAP)

84.1

NA

  1. Lower and upper reference limits are shown according to the World Health Organization standards (WHO 2010) [20]
  2. NA Not available