Skip to main content
Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: A loss-of-function variant in SSFA2 causes male infertility with globozoospermia and failed oocyte activation

Fig. 5

Clinical features of the couple undergoing ICSI treatment. A Eighteen to 19 hours after regular ICSI, the majority of eggs failed to be fertilized by microscopy, and the black arrow indicates pronuclei. B Forty-two to 44 hours after regular ICSI, three zygotes developed into three poor-quality 4-cell embryos. C, D Immunofluorescence and western blot analysis showed that PLCζ expression in patient sperm was significantly reduced compared to the healthy control (green, PLCζ; blue, DAPI; scale bars, 1 μm)

Back to article page