Fig. 6From: The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female ratsEffects of IGFBP-5 on serum hormone in AVO groups of female rats (n = 6/group) a-e The concentration of E2, P4, FSH, LH and IGF-1 in serum at VO after IGFBP-5 ICV injection (AVO). ** indicates a very significant difference (P < 0.01); * indicates a significant difference (P < 0.05)Back to article page