Fig. 5
From: The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats
The effect of IGFBP-5 on puberty-relative gene expression and the time of vaginal opening in MA experiments of female rats (n = 6/group). a The expression level of puberty-related gene mRNA at matched age in the rat hypothalamus (MA). b The expression level of Igf-1,Igf-1r,Igfbp-5,Fshβ and Lhβ mRNA at matched age in the rat pituitary(MA). c The expression level of Igf-1,Igf-1r and Igfbp-5 mRNA at matched age in the rat ovary (MA). ** indicates a very significant difference (P < 0.01); * indicates a significant difference (P < 0.05)