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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes

Fig. 4

Significant expression changes of genes in Ezh2Short oocytes. A Volcano plot of differentially expressed genes (DEGs) in Ezh2Short oocytes. The 585 up-regulated genes are marked in red; 179 down-regulated genes are marked in blue. B Heatmap of the top 25 up/down-regulated genes in Ezh2Short oocytes. C Real-time RT-PCR verified changed expression of Cps1, Yy1 and Xist mRNA levels. **P < 0.001, ****P < 0.0001. D The gene ontology analysis of DEGs (upper, down-regulated genes; lower, up-regulated genes). E The rich factor by KEGG enrichment analysis for the DEGs in Ezh2Short oocytes (upper, down-regulated genes; lower, up-regulated genes). F Volcano plot of differentially expressed transposable elements (TEs) in Ezh2Short oocytes. Up-regulated TEs are marked in red; down-regulated TEs are marked in blue. G. Heatmap of up/down-regulated TEs in Ezh2Short oocytes

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