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Table 4 Joint association of maternal age and pre-pregnancy body mass index with risk of LGA and preterm birth

From: Association of maternal pre-pregnancy body mass index with birth weight and preterm birth among singletons conceived after frozen-thawed embryo transfer

 

LGA

Preterm birth

 

Underweight

(BMI < 18.5 kg/m2)

Normal weight

(BMI 18.5-24.9 kg/m2)

Overweight

(BMI 25.0-29.9 kg/m2)

Underweight

(BMI < 18.5 kg/m2)

Normal weight

(BMI 18.5-24.9 kg/m2)

Overweight

(BMI 25.0-29.9 kg/m2)

Age group, years

 < 30

0.59 (0.46,0.75)

1.20 (1.05,1.38)

1.85 (1.49,2.29)

0.66 (0.47,0.92)

0.92 (0.76,1.12)

1.30 (0.96,1.76)

 30-34

0.50 (0.39,0.65)

1.08 (0.95,1.23)

2.00 (1.66,2.42)

0.71 (0.51,0.99)

0.89 (0.74,1.07)

1.43 (1.09,1.86)

 35-37

0.85 (0.60,1.22)

1.00(Ref)

1.95 (1.50,2.54)

0.86 (0.53,1.40)

1.00(Ref)

1.51 (1.05,2.18)

 ≥ 38

0.58 (0.30,1.13)

0.92 (0.77,1.11)

1.86 (1.34,2.58)

0.65 (0.26,1.61)

1.14 (0.90,1.45)

1.76 (1.15,2.71)

  1. Women aged 35–37 years who were a normal weight before pregnancy were the reference group
  2. Primary infertility, parity, type of ART procedure, number of embryos transferred, embryo stage at transfer, infertility diagnosis (tubal factor, ovulation dysfunction, diminished ovarian reserve, endometriosis, uterine factor, male factor, unexplained or others factors), offspring gender, year of birth were adjusted for in models
  3. BMI Body mass index (calculated as weight in kilograms divided by height in meters squared), LGA Large for gestational age (defined as birth weight above the 90th percentile for gestational age). Preterm birth was defined as delivery occurring before 37 weeks of gestation
  4. The model included generalized estimating equations to account for clustering by patient
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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