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Table 1 Comparison of general factors between the cSLE and aSLE groups

From: Characteristics of childhood-onset systemic lupus erythematosus in pregnancy and its association with pregnancy outcomes: a retrospective comparative cohort study

Characteristics

cSLE (N = 22)

aSLE (N = 145)

P value

Gestational age, years, median (IQR)

23.50 (20.75, 29.00)

29.00 (26.00, 32.00)

< 0.001

SLE duration, years, median (IQR)

10.00 (5.75, 13.50)

5.00 (3.00, 7.00)

< 0.001

Pre-pregnancy BMI, kg/m2, median (IQR)

19.27 (17.49, 22.09)

20.48 (18.72, 22.04)

0.086

Native place

  

0.467

 Guangdong province

16 (72.7%)

94 (64.8%)

 

 Others

6 (27.3%)

51 (35.2%)

 

Employment

  

0.758

 Unemployed

15 (68.2%)

94 (64.8%)

 

 Employed

7 (31.8%)

51 (35.2%)

 

Parity

  

0.022

 Primiparous

19 (86.4%)

89 (61.4%)

 

 Multiparous

3 (13.6%)

56 (38.6%)

 

History of medicine or food allergic

3 (13.6%)

36 (24.8%)

0.248

History of adverse pregnancy and birth

3 (13.6%)

30 (20.7%)

0.626

History of caesarean section

2 (9.1%)

21 (14.5%)

0.725

First pregnancy after diagnosis of SLE

19 (86.4%)

121 (83.4%)

0.972

SLE in remission for < 6 months before pregnancy

1 (4.5%)

14 (9.7%)

0.703

LN before pregnancy

14 (63.6%)

48 (33.1%)

0.006

  1. SLE systemic lupus erythematosus, LN lupus nephritis, cSLE childhood-onset systemic lupus erythematosus, aSLE adult-onset systemic lupus erythematosus, BMI body mass index, IQR interquartile range