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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion

Fig. 1

miR-135a-5p offers promise as a diagnostic biomarker for unexplained SA. (a) Heat maps demonstrating relative miR-135a-5p expression in first-trimester villous tissue samples from NP (n = 5) and URSA (n = 5) patients. (b) MiR-135a-5p expression in the villous tissues from NP (n = 32) and USM (n = 32) patients. (c) MiR-135a-5p offered good diagnostic potential for USM. (d) MiR-135a-5p expression in the villous tissues from NP (n = 18) and URSA (n = 18) patients. (e) MiR-135a-5p offered good diagnostic potential for URSA. NP: normal pregnancy; SA: spontaneous abortion; USM: unexplained sporadic miscarriage; URSA: unexplained recurrent spontaneous abortion; ROC: Receiver operating characteristic; AUC: Area under the curve. *P < 0.05, **P < 0.01, *** P < 0.001

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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