Table 4 Discrimination of morphology-only model in predicting blastocyst formation in different patient subgroup
From: Does conventional morphological evaluation still play a role in predicting blastocyst formation?
Training set | Validation set | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Subgroup | n | Prevalence(95%CI) | AUC(95%CI) | PPV(95%CI) | NPV(95%CI) | Accuracy(95%CI) | n | Prevalence(95%CI) | AUC(95%CI) | PPV(95%CI) | NPV(95%CI) |
Insemination | |||||||||||
IVF | 70,073 | 0.592(0.588–0.596) | 0.771(0.767–0.775) | 0.753(0.749–0.757) | 0.697(0.691–0.702) | 0.733(0.73–0.736) | 8615 | 0.615(0.605–0.625) | 0.794(0.784–0.804) | 0.769(0.759–0.78) | 0.722(0.706–0.739) |
ICSI | 26,305 | 0.526(0.52–0.532) | 0.767(0.761–0.772) | 0.712(0.705–0.719) | 0.717(0.709–0.725) | 0.714(0.709–0.72) | 3155 | 0.546(0.529–0.564) | 0.781(0.765–0.797) | 0.733(0.713–0.753) | 0.719(0.694–0.743) |
Female age | |||||||||||
age < 35 | 82,599 | 0.581(0.578–0.584) | 0.775(0.772–0.779) | 0.75(0.747–0.754) | 0.698(0.693–0.703) | 0.731(0.728–0.734) | 9603 | 0.604(0.594–0.614) | 0.798(0.789–0.807) | 0.771(0.76–0.781) | 0.717(0.702–0.733) |
age≧35 | 13,779 | 0.532(0.524–0.541) | 0.749(0.741–0.758) | 0.697(0.688–0.707) | 0.732(0.72–0.744) | 0.711(0.703–0.718) | 2167 | 0.565(0.544–0.586) | 0.767(0.747–0.787) | 0.716(0.693–0.739) | 0.741(0.709–0.773) |
Ovarian response | |||||||||||
oocyte≦4 | 1677 | 0.592(0.568–0.615) | 0.741(0.716–0.765) | 0.741(0.714–0.767) | 0.66(0.623–0.697) | 0.711(0.689–0.732) | 434 | 0.585(0.539–0.632) | 0.752(0.706–0.798) | 0.717(0.665–0.77) | 0.662(0.587–0.738) |
oocyte > 4 | 94,701 | 0.574(0.571–0.577) | 0.772(0.769–0.775) | 0.743(0.739–0.746) | 0.704(0.699–0.709) | 0.728(0.725–0.731) | 11,336 | 0.597(0.588–0.606) | 0.794(0.785–0.802) | 0.762(0.753–0.772) | 0.724(0.71–0.738) |