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Fig. 7 | Reproductive Biology and Endocrinology

Fig. 7

From: Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis

Fig. 7

Effects of Exo-AFAP1-AS1/miR-15a-5p/BCL9 on EMS progression in nude mice. A RT-qPCR to detect the expression of AFAP1-AS1 in ESC-Exo after silencing of AFAP1-AS1. B Change in volume of ectopic lesions in EMS nude mice after Exo-sh-NC and Exo-sh-AFAP1-AS1 treatment. C Change in weight of ectopic lesions in EMS after Exo-sh-NC and Exo-sh-AFAP1-AS1 treatment. D RT-qPCR to analyze the expression of AFAP1-AS1, BCL9 and miR-15a-5p in the ectopic tissues of EMS mice after Exo-sh-NC and Exo-sh-AFAP1-AS1 treatment. E IHC to detect the expression of AFAP1-AS1, BCL9, and miR-15a-5p in the ectopic tissues of EMS mice after Exo-sh-NC and Exo-sh-AFAP1-AS1 treatment. * p < 0.05 indicates the comparison between two groups. A total of 10 nude mice per treatment

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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