Fig. 3
From: The role of SK3 in progesterone-induced inhibition of human fallopian tubal contraction
Effect of apamin on progesterone-induced inhibition of the spontaneous contraction of the hFTSM. A-B The effect of increasing concentrations of progesterone (A) and 10− 6 M progesterone (B) on the amplitude (a) and frequency (b) of spontaneous contraction of hFTSM from the Non-EP group pretreated with apamin. C-D The effect of increasing concentrations of progesterone (C) and 10− 6 M progesterone (D) on the amplitude (a) and frequency (b) of spontaneous contraction of the hFTSM from the EP group pretreated with apamin. E-F Comparison of the effects of increasing concentrations of progesterone € and 10− 6 M progesterone (F) on the amplitude (a) and frequency (b) of spontaneous contraction of the hFTSM pretreated with apamin between the two groups. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001 (significant difference detected within a group as compared with the baseline amplitude/frequency. #, P<0.05; ##, P<0.01; ###, P<0.001; ####, P<0.0001 (significant difference detected between apamin-pretreated and vehicle-pretreated group). ++, P<0.01; ++++, P<0.0001 (significant difference detected between Non-EP and EP groups)