Table 2 Semen parameters and sperm morphology of men harbouring homozygous SPAG6 variants
From: Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
Subject | F1 II-1 | F2 II-1 | Reference Valuesa | ||
|---|---|---|---|---|---|
Age | 29 | 26 | |||
Semen parameter | Sample 1 | Sample 2 | Sample 1 | Sample 2 | |
Semen volume (mL) | 2.2 | 3.5 | 3.4 | 3.6 | > 1.5 |
Concentration (106/mL) | 107.0 | 63.9 | 16.8 | 27.4 | > 15.0 |
Motility (%) | 2.0 | 2.7 | 0 | 0 | > 40.0 |
Progressive motility (%) | 0.3 | 0.5 | 0 | 0 | > 32.0 |
Viability (%) | 66 | NA | 61 | NA | > 58.0 |
Sperm Morphology | |||||
Normal flagella (%) | 3.2 | 4.1 | > 23.0 | ||
Absent flagella (%) | 4.5 | 7.1 | < 5.0 | ||
Short flagella (%) | 55.3 | 47.6 | < 1.0 | ||
Coiled flagella (%) | 32.5 | 39.2 | < 17.0 | ||
Angulation (%) | 3.5 | 1.5 | < 13.0 | ||
Irregular caliber (%) | 1.0 | 0.5 | < 2.0 | ||