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Table 1 Effects of CdCl2 alone and in combination with letrozole (CdCl2 + letrozole) on the body weight and absolute and relative testes weights of male mice

From: Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice

Groups

Body weight

TW

TW/BW ratio (mg/g)

Initial BW

Final BW

Control

30.52 ± 0.41

35.97 ± 0.57

0.25 ± 0.01

0.68 ± 0.02

Cd (4 mg/kg)

30.99 ± 0.64

33.55 ± 0.53*

0.24 ± 0.01

0.73 ± 0.03

Cd + letrozole (4 + 0.25 mg/kg)

30.85 ± 0.21

34.89 ± 0.31#

0.25 ± 0.01

0.72 ± 0.03

  1. BW Body weight, TW Testis weight. Means ± SEM of five animals in each group. Compared with control group, *p < 0.05; compared with the Cd group, #p < 0.05