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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells

Fig. 6

GDF-11 expression levels are not varied in hGL cells and follicular fluid between normal and PCOS patients. A, and B, Follicular fluid samples were collected from 36 non-PCOS and 36 PCOS patients of similar age. The body mass index (BMI), antral follicle count (AFC), and basal levels of hormones in serum including follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P4), and testosterone (T) were measured. C, GDF-11 protein levels in follicular fluid samples were measured by ELISA. D, GDF-11 mRNA levels in hGL cells obtained from 12 non-PCOS and 12 PCOS patients were measured by RT-qPCR. The clinical results are expressed as the mean ± SD

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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