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Table 4 Obesity during childhood categorized by maternal presence of polycystic ovary syndrome (PCOS) and exposure to metformin

From: Pregnancy, perinatal and childhood outcomes in women with and without polycystic ovary syndrome and metformin during pregnancy: a nationwide population-based study

 

PCOS(−)

Metformin(−)

PCOS(−)

Metformin(+)

PCOS(+)

Metformin(−)

PCOS(+)

Metformin(+)

PCOS(−)

Metformin(+)

PCOS(+)

Metformin(−)

PCOS(+)

Metformin(+)

PCOS(−)

Metformin(+)

PCOS(+)

Metformin(−)

PCOS(+)

Metformin(+)

 

Number (%)

Crude, HR (95% CI)

Adjusted, HR (95% CI)a

 

991,019

864

21,385

347

      

Obesity

 Yes

7589 (0.77)

19 (2.2)

319 (1.49)

6 (1.73)

4.03 (2.57–6.31)

2.37 (2.11–2.66)

2.48 (1.12–5.49)

1.67 (1.05–2.65)

1.61 (1.44–1.81)

1.13 (0.51–2.53)

 No

983,430 (99.23)

845 (97.8)

21,066 (98.51)

341 (98.27)

      
  1. Abbreviations: HR Hazard Ratio, CI Confidence Interval
  2. a Adjusted by maternal body mass index, maternal age, year of birth, cigarette consumption, assisted reproduction, parity, gestational diabetes, and diabetes mellitus
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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