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Table 4 Obesity during childhood categorized by maternal presence of polycystic ovary syndrome (PCOS) and exposure to metformin

From: Pregnancy, perinatal and childhood outcomes in women with and without polycystic ovary syndrome and metformin during pregnancy: a nationwide population-based study

  PCOS(−)
Metformin(−) 		PCOS(−)
Metformin(+) 		PCOS(+)
Metformin(−) 		PCOS(+)
Metformin(+) 		PCOS(−)
Metformin(+) 		PCOS(+)
Metformin(−) 		PCOS(+)
Metformin(+) 		PCOS(−)
Metformin(+) 		PCOS(+)
Metformin(−) 		PCOS(+)
Metformin(+)
  Number (%) Crude, HR (95% CI) Adjusted, HR (95% CI)a
  991,019 864 21,385 347       
Obesity
 Yes 7589 (0.77) 19 (2.2) 319 (1.49) 6 (1.73) 4.03 (2.57–6.31) 2.37 (2.11–2.66) 2.48 (1.12–5.49) 1.67 (1.05–2.65) 1.61 (1.44–1.81) 1.13 (0.51–2.53)
 No 983,430 (99.23) 845 (97.8) 21,066 (98.51) 341 (98.27)       
  1. Abbreviations: HR Hazard Ratio, CI Confidence Interval
  2. a Adjusted by maternal body mass index, maternal age, year of birth, cigarette consumption, assisted reproduction, parity, gestational diabetes, and diabetes mellitus
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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