Table 1 Maternal characteristics of all pregnancies in Sweden (2006—2016) categorized by presence or absence of polycystic ovary syndrome (PCOS) and use of metformin
|  | PCOS (−) Metformin (−) n (%) | PCOS (−) Metformin (+) n (%) | PCOS (+) Metformin (−) n (%) | PCOS (+) Metformin (+) n (%) | ||||
|---|---|---|---|---|---|---|---|---|
994,102 | 870 | 21,486 | 347 | |||||
Maternal age | ||||||||
  < 25 | 142,228 | (14.3) | 58 | (6.7) | 2875 | (13.4) | 34 | (9.8) |
 25–29 | 296,675 | (29.8) | 185 | (21.3) | 7108 | (33.1) | 105 | (30.3) |
 30–34 | 338,465 | (34) | 305 | (35.1) | 7547 | (35.1) | 122 | (35.2) |
  ≥ 35 | 216,734 | (21.8) | 322 | (37.0) | 3956 | (18.4) | 86 | (24.8) |
Maternal BMI (Kg/m2) | ||||||||
  < 20 | 103,661 | (10.4) | 14 | (1.6) | 1600 | (7.4) | 9 | (2.6) |
 20–24.9 | 518,187 | (52.1) | 152 | (17.5) | 8462 | (39.4) | 60 | (17.3) |
 25–29.9 | 249,843 | (25.1) | 234 | (26.9) | 6022 | (28) | 92 | (26.5) |
  ≥ 30 | 122,411 | (12.3) | 470 | (54) | 5402 | (25.1) | 186 | (53.6) |
Parity | ||||||||
 Multiparous | 556,148 | (55.9) | 555 | (63.8) | 10,332 | (48.1) | 149 | (42.9) |
 Primiparous | 437,954 | (44.1) | 315 | (36.2) | 11,154 | (51.9) | 198 | (57.1) |
Cigarette Consumption | ||||||||
 Yes | 59,804 | (6) | 47 | (5.4) | 1228 | (5.7) | 20 | (5.8) |
 No | 934,298 | (94) | 823 | (94.6) | 20,258 | (94.3) | 327 | (94.2) |
Assisted Reproduction | ||||||||
 Yes | 28,376 | (2.9) | 53 | (6.1) | 2357 | (11) | 34 | (9.8) |
 No | 965,726 | (97.1) | 817 | (93.9) | 19,129 | (89) | 313 | (90.2) |
Diabetes Mellitus | ||||||||
 Yes | 5695 | (0.6) | 273 | (31.4) | 304 | (1.4) | 49 | (14.1) |
 No | 988,407 | (99.4) | 597 | (68.6) | 21,182 | (98.6) | 298 | (85.9) |
Gestational Diabetes | ||||||||
 Yes | 11,578 | (1.2) | 282 | (32.4) | 559 | (2.6) | 26 | (7.5) |
 No | 982,524 | (98.8) | 588 | (67.6) | 20,927 | (97.4) | 321 | (92.5) |