Skip to main content

Table 1 Baseline characteristics between different endometrial preparation groups

From: Gonadotropin-releasing hormone agonist downregulation combined with hormone replacement therapy improves the reproductive outcome in frozen–thawed embryo transfer cycles for patients of advanced reproductive age with idiopathic recurrent implantation failure

Characteristic

GnRH agonist-HRT

HRT

NC

P value

(n = 290)

(n = 194)

(n = 65)

female age(y)

38.7 ± 2.19

39.14 ± 2.2

38.74 ± 1.96

0.083

BMI (kg/m2)

22.37 ± 2.74

22.66 ± 2.77

22.13 ± 2.48

0.313

ET cycle number

3.43 ± 0.75

3.42 ± 0.71

3.52 ± 0.9

0.609

Interval between fresh and frozen transfer(m)

6.41 ± 5.92

6.11 ± 6.57

5.75 ± 4.65

0.688

bFSH (IU/L)

7.95 ± 2.97

8.28 ± 2.96

8.07 ± 3.17

0.509

Infertility duration in years (y)

5.48 ± 4.10

5.27 ± 4.28

5.78 ± 3.98

0.670

Infertility type (n, %)

   

0.272

 Primary infertility

75 (25.86)

46 (23.71)

22 (33.85)

 

 Secondary infertility

215 (74.14)

148 (76.29)

43 (66.15)

 

Fertilization type (n, %)

   

0.028 *

 IVF

208 (71.70)

135 (69.60)

49 (75.40)

 

 ICSI

78 (26.90)

56 (28.90)

11 (16.90)

 

 IVF + ICSI

4 (1.40)

3 (1.50)

5 (7.70)

 

Progesterone on the administration day (ng/ml)

0.38 ± 0.29

0.54 ± 0.47

 

0.000 *

Endometrial thickness on the day of transfer (mm)

10.34 ± 1.68

9.79 ± 1.54

10.78 ± 2.25

0.000 *

No. of transferred embryos (n, %)

   

0.055

 1

84 (28.97)

70 (36.08)

29 (44.62)

 

 2

193 (66.55)

116 (59.79)

31 (47.69)

 

 3

13 (4.48)

8 (4.12)

5 (7.69)

 

Type of embryo transferred(n, %)

   

0.074

 Cleavage stage embryo

130 (44.83)

107 (55.15)

34 (52.31)

 

 Blastocyst

160 (55.17)

87 (44.85)

31 (47.69)

 
  1. Values are means±SD or number (percentage) of patients. *P < 0.05 for t test or chi-squared test;
  2. Abbreviations: BMI Body mass index; bFSH basal follicle-stimulating hormone; IVF In vitro fertilization; ICSI Intracytoplasmic sperm injection