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Fig. 7 | Reproductive Biology and Endocrinology

Fig. 7

From: Zinc transporter ZIP12 maintains zinc homeostasis and protects spermatogonia from oxidative stress during spermatogenesis

Fig. 7

Schematic representation of ZIP12 function in spermatogenesis. The zinc transporter ZIP12 is highly expressed in the testis, especially in spermatogonia and spermatozoa. It mediates zinc influx into cytosol and is involved in maintaining intracellular zinc content at levels that are adequate to play a key role in suppressing environmental stress-induced rises in ROS from reaching levels that may be injurious to spermatogonia and sperm quality

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