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Table 3 Effects of SPM treatments on the body weight, testis weight and sperm parameters in diabetic mice

From: Effect of spermidine on ameliorating spermatogenic disorders in diabetic mice via regulating glycolysis pathway

Group

Body weight (g)

Testis weight (mg)

Sperm count (×107)

Abnormal sperm number (×107)

Abnormal sperm rate (%)

Pre-induction

After treatment

Control

21.08 ± 0.38

25.36 ± 1.54

173.40 ± 4.65

6.86 ± 0.57

1.81 ± 0.32

25.17 ± 3.91

DM

19.52 ± 0.82*

15.40 ± 1.62**

132.40 ± 20.1*

3.60 ± 1.63**

3.00 ± 1.06*

69.09 ± 22.07**

DM + SPM 2.5 mg/kg

19.28 ± 0.87**

20.14 ± 1.06##

171.20 ± 10.85#

5.70 ± 1.36#

1.50 ± 0.53#

32.15 ± 7.54##

DM + SPM 5 mg/kg

19.38 ± 0.79**

22.66 ± 1.18##

173.53 ± 7.90#

6.15 ± 0.63#

1.20 ± 0.41##

25.17 ± 3.91

  1. *P < 0.05; **P<0.01 vs. Control; #P < 0.05; ##P<0.01 vs. DM