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Table 3 Clinical outcomes of ICSI for the SLO3-mutated Man

From: Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations

 

SLO3-mutated Man

OAT as Controls

Male age (years)

29

30.1 ± 4.9

Female age (years)

34

28.4 ± 4.2

No. of ICSI cycles

1

301

No. of oocytes injected

15

11 (1, 34)

Fertilization rate (%) (and number)

100 (15/15)

83.3 (12.5, 100.0)

(3219/4077)

Cleavage rate (%) (and number)

100 (15/15)

100.0 (66.7, 100.0)

(3188/3219)

8-Cell formation rate (%) (and number)

73 (11/15)

70.6 (10.5, 100.0)

Blastocyst formation rate (%) (and number)

73 (11/15)

60.0 (0, 100.0)

No. of transfer cycles

1

301

Number of embryos transferred per cycle

2

2 (1, 2)

Implantation rate (%)

50

47.9 (229/478)

Clinical pregnancy rate (%)

100

57.1 (172/301)

Miscarriage rate (%)

0

11.6 (20/172)

  1. OAT Oligoasthenoteratozoospermia; The number of OAT couples is 301