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Table 2 Semen Parameters and Sperm Morphology of the SLO3-mutated Man

From: Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations

Subject

A-132

Reference Values

Semen Parameters

 Semen Volume (mL)

4.3

> 1.5a

 Concentration (106/mL)

12.7

> 15.0a

 Motility (%)

31.9

> 40.0a

 Progressive motility (%)

4.8

> 32.0a

Sperm Morphology

 Normal sperm (%)

2.3 (5/215)

> 4.0a

 Small acrosome (%)

61.4 (132/215)

< 5.0b

 Abnormal midpieces (%)

35.3 (76/215)

< 11.4c

 Coiled flagella (%)

50.2 (108/215)

< 17.0b

 Abnormal sperm (%)

97.7

<96a

  1. aReference limits according to the 5th WHO standards [14]
  2. bReference limits according to the distribution range of morphologically normal spermatozoa observed in 926 fertile subjects [17]
  3. cReference limits according to the distribution range of morphologically normal spermatozoa observed in 10 fertile subjects
  4. At least 200 spermatozoa were observed for morphology analysis