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Table 1 Clinical characteristics and cycle outcomes of recruited subjects with PCOS or without PCOS

From: Elevated SAA1 promotes the development of insulin resistance in ovarian granulosa cells in polycystic ovary syndrome

 

Non-PCOS without IR

Non-PCOS with IR

PCOS without IR

PCOS with IR

No.

22

22

22

22

Age (y)

29.6 ± 0.93

29.8 ± 0.81

29.8 ± 0.7

28.1 ± 0.96

BMI (kg/m2)

20.7 ± 0.41

26 ± 0.45 *#

23.7 ± 0.66

26.7 ± 0.85*#

WBC (counts*109)

5.6 ± 0.4

6.8 ± 0.3

6.3 ± 0.4

7.2 ± 0.4*

CRP (mg/L)

0.3 ± 0.4

1.1 ± 0.2

1.6 ± 0.5

2.2 ± 0.5*

Basal FSH (mIU/ml)

6.1 ± 0.6

6.1 ± 0.45

5.8 ± 0.3

5.5 ± 0.5

Basal LH (mIU/ml)

4.5 ± 0.47

3.9 ± 0.45

8.5 ± 0.94 *&

7.1 ± 0.98 *&

LH/FSH

0.7 ± 0.07

0.7 ± 0.1

1.5 ± 0.14 *&

1.2 ± 0.14 *&

T (nM/L)

0.7 ± 0.1

0.85 ± 0.12

1.1 ± 0.16 *&

1.2 ± 0.34*&

AMH (ng/ml)

3.8 ± 0.4

4.6 ± 0.3

11.1 ± 1.4 *&

8.7 ± 1.1*&

Fasting glucose (mM/L)

5.1 ± 0.07

5.4 ± 0.13

4.8 ± 0.14

5.2 ± 0.12

Fasting insulin (IU/ml)

4.8 ± 0.69

14 ± 1.05 *#

6.8 ± 0.53

18.9 ± 2.8 *#

HOMA-IR

1.1 ± 0.15

3.3 ± 0.24 *#

1.43 ± 0.11

4.3 ± 0.61*#

No. of oocytes retrieved

12.6 ± 1.9

12.1 ± 1.6

18.6 ± 2 *&

20.1 ± 3.3 *&

IVF percentage (%)

50

62.5

62.5

56.25

ICSI percentage (%)

50

37.5

37.5

43.75

Fertilization rate

0.78 ± 0.04

0.72 ± 0.04

0.75 ± 0.04

0.63 ± 0.05 *

Cleavage rate

0.99 ± 0.008

0.99 ± 0.009

0.98 ± 0.01

0.96 ± 0.02 *

High-quality embryo rate

0.65 ± 0.08

0.59 ± 0.07

0.57 ± 0.06

0.41 ± 0.05 *

  1. Data are mean ± SEM values
  2. * P < 0.05 vs. Non-PCOS without IR. & P < 0.05 vs. Non-PCOS with IR. # P < 0.05 vs. PCOS without IR