Fig. 4
From: Pak2 reduction induces a failure of early embryonic development in mice
Pak2 knockdown elevates ROS levels in embryos. (A) Representative images of CM-H2DCFDA fluorescence (green) in 2-cell embryos from control and Pak2-KD groups (n = 24 for control group and n = 28 for Pak2-KD group; scale bars, 120 μm). (B) Quantitative analysis of fluorescence intensity in control and Pak2-KD embryos (7.9 ± 1.39, n = 24 vs. 15.8 ± 1.41, n = 28, respectively). Data are expressed as the mean ± SD from three independent experiments. *Significantly different (p < 0.05). Pak2, p21-activated kinase 2; Pak2-KD, Pak2 knockdown; SD, standard deviation; ROS, reactive oxygen species