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Table 2 Subgroup analysis in testosterone and DHEA

From: The effects of statins on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

Subgrouped by

No. of trials

WMD (95% CI)

P Value

P for heterogeneity

I2 (%)

P for between Subgroup heterogeneity

Testosterone

 total

9

-0.47[−0.76,-0.18]

0.002

0.002

68

 

 Statin type

     

0.86

  Simvastatin

6

-0.48 [−0.77, − 0.18]

0.002

0.002

66

 

  Atorvastatin

3

−0.39 [−1.38, 0.61]

0.45

0.007

80

 

 Contol type

     

0.90

  Placebo

5

-0.39 [−0.86, 0.09]

0.11

0.008

71

 

  Metformin

3

−0.43 [− 0.84, − 0.02]

0.04

0.06

65

 

DHEA

 total

7

−0.51 [− 0.97, − 0.05]

0.03

< 0.001

84

 

 Statin type

     

0.79

  Simvastatin

5

−0.46 [−1.02, 0.09]

0.10

< 0.001

89

 

  Atorvastatin

2

−0.62 [−1.70, 0.45]

0.25

< 0.001

67

 

 Contol type

     

0.70

  Placebo

3

−0.49 [−1.44, 0.46]

0.31

< 0.001

93

 

  Metformin

3

−0.70 [−1.20, − 0.21]

0.005

0.15

47

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