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Table 2 Logistic regression analysis of TI from tHa to tHd and live birth rate after fresh cleaved embryo transfer

From: Characteristics of the cytoplasmic halo during fertilisation correlate with the live birth rate after fresh cleaved embryo transfer on day 2 in minimal ovarian stimulation cycles: a retrospective observational study

 

Univariate logistic regression analysis

Multivariate logistic regression analysis

OR

95% CI

P-value

AUC

aOR

95% CI

P-value

AUC

Female age

0.832

0.796–0.868

< 0.0001

0.704

0.827

0.778–0.878

<  0.0001

0.732

Male age

0.930

0.901–0.959

< 0.0001

0.611

1.018

0.978–1.060

0.3681

 

Ovarian stimulation

   

0.594

    

 Natural

Reference

–

  

Reference

–

  

 Clomiphene citrate

0.401

0.263–0.618

< 0.0001

 

0.732

0.455–1.177

0.1979

 

 Letrozole

1.250

0.657–2.360

0.4938

 

1.046

0.526–2.077

0.8987

 

Insemination method

   

0.506

    

 cIVF

Reference

–

  

Reference

–

  

 ICSI

0.943

0.666–1.347

0.7472

 

0.927

0.629–1.363

0.6990

 

Blastomere number

1.081

0.986–1.185

0.0983

0.535

1.100

0.997–1.214

0.0575

 

Morphological grade

   

0.550

    

 1

Reference

–

–

 

Reference

–

–

 

 2

1.212

0.731–2.049

0.4587

 

1.509

0.867–2.625

0.1452

 

 3

0.986

0.618–1.614

0.9560

 

1.138

0.681–1.899

0.6214

 

 4

0.981

0.049–6.974

0.9869

 

0.754

0.103–5.734

0.1656

 

TI from tHa to tHd

0.879

0.825–0.934

< 0.0001

0.593

0.879

0.817–0.946

0.0004

 
  1. aOR Adjusted odds ratio, AUC Area under the curve, CI Confidence interval, cIVF Conventional in vitro fertilisation, ICSI Intracytoplasmic sperm injection, OR Odds ratio, tHa Time of halo initiation, tHd Time when the halo phenomenon disappeared, TI Time interval