| Halo-positive | Halo-negative | P-value |
---|---|---|---|
Patients, n | 866 | 36 | Â |
Female age (y) | 36.8 ± 0.1 | 38.2 ± 0.6 | 0.0517 |
Male age (y) | 39.3 ± 0.2a | 43.1 ± 1.2b | 0.0001 |
Previous embryo transfer cycles, n | 0.51 ± 0.01 | 0.50 ± 0.01 | 0.8992 |
Cause of infertility | Â | Â | 0.9447 |
 Ovulation, n (%) | 30 (3.5) | 1 (2.8) |  |
 Tubal factor, n (%) | 16 (1.9) | 1 (2.8) |  |
 Endometrial factor, n (%) | 70 (8.1) | 4 (11.1) |  |
 Male factor, n (%) | 112 (12.9) | 3 (8.3) |  |
 Combined, n (%) | 20 (2.3) | 1 (2.8) |  |
 Unexplained, n (%) | 618 (71.4) | 26 (72.2) |  |
Ovarian stimulation | Â | Â | 0.8694 |
 Natural cycle, n (%) | 120 (13.9) | 4 (11.1) |  |
 Clomiphene citrate cycle, n (%) | 685 (79.1) | 29 (80.6) |  |
 Letrozole cycle, n (%) | 61 (7.0) | 3 (8.3) |  |
Oestradiol level on day of the trigger (pg/mL) | 777.6 ± 14.1 | 717.0 ± 63.4 | 0.3925 |
Progesterone level on day of the trigger (ng/mL) | 0.4 ± 0.0 | 0.4 ± 0.0 | 0.2016 |
Oocytes retrieved, n | 1.9 ± 0.0 | 1.9 ± 0.1 | 0.8497 |
Oocyte diameter | 113.5 ± 0.2 | 113.3 ± 0.6 | 0.7871 |
Total sperm number (×106) | 173.8 ± 6.1 | 155.7 ± 21.9 | 0.5539 |
Motile sperm number (×106) | 93.1 ± 3.9 | 68.9 ± 10.2 | 0.2067 |
Motile sperm rate (%) | 50.7 ± 0.6 | 46.6 ± 3.0 | 0.1883 |
Abnormal sperm number (×106) | 164.6 ± 5.8 | 147.4 ± 20.7 | 0.5477 |
Abnormal sperm rate (%) | 94.8 ± 0.1 | 94.8 ± 0.3 | 0.8384 |
Embryos transferred, n | 866 | 36 | Â |
Blastomeres in embryos transferred | 5.8 ± 0.1 | 5.3 ± 0.3 | 0.0802 |
Morphological grade based on Veeck’s criteria | |||
 1, n (%) | 133 (15.4) | 4 (11.1) | 0.4866 |
 2, n (%) | 250 (28.9) | 9 (25.0) | 0.6152 |
 3, n (%) | 478 (55.2) | 21 (58.3) | 0.7107 |
 4, n (%) | 5 (0.6)a | 2 (5.6)b | 0.0009 |
Clinical pregnancy, n (%) | 251 (29.0) | 6 (16.7) | 0.1087 |
Ongoing pregnancy, n (%) | 215 (24.8) | 4 (11.1) | 0.0600 |
Live birth, n (%) | 183 (21.1)a | 2 (5.6)b | 0.0233 |
Miscarriage, n (%) | 61 (24.3)a | 4 (66.7)b | 0.0183 |