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Fig. 7 | Reproductive Biology and Endocrinology

Fig. 7

From: Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

Fig. 7

Pretreatment with BMP2 suppresses GDF8-induced phosphorylation of SMAD2/3 in SVOG and primary hGL cells. A and B, the effects of pretreatment of BMP2 on the GDF8-induced increases in the phosphorylated protein levels of SMAD2 (A) and SMAD3 (B) in SVOD cells. C and D, the effects of pretreatment of BMP2 on the GDF8-induced increases in the phosphorylated protein levels of SMAD2 (A) and SMAD3 (B) in primary hGL cells. The results are expressed as the mean ± SEM of at least three independent experiments, and values without common letters are considered significantly different (P < 0.05). GDF8, growth differentiation factor 8

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