Fig. 7From: Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cellsPretreatment with BMP2 suppresses GDF8-induced phosphorylation of SMAD2/3 in SVOG and primary hGL cells. A and B, the effects of pretreatment of BMP2 on the GDF8-induced increases in the phosphorylated protein levels of SMAD2 (A) and SMAD3 (B) in SVOD cells. C and D, the effects of pretreatment of BMP2 on the GDF8-induced increases in the phosphorylated protein levels of SMAD2 (A) and SMAD3 (B) in primary hGL cells. The results are expressed as the mean ± SEM of at least three independent experiments, and values without common letters are considered significantly different (P < 0.05). GDF8, growth differentiation factor 8Back to article page