Fig. 3From: Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic ratsICA administration upregulated the expression of PCNA in the testis of diabetic rats. A Immunohistochemical analysis of PCNA expression. Red arrows point to representatively positive signals of spermatogonia. B Quantification of PCNA positive cells from different groups. C mRNA expression analysis of Pcna with qRT-PCR. The upper panes in A mean PCNA positive cells, and the lower panes present negative controls. N = 6, Bars assigned with different superscripts mean significant difference (p < 0.05)Back to article page