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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: microRNA-194 is increased in polycystic ovary syndrome granulosa cell and induce KGN cells apoptosis by direct targeting heparin-binding EGF-like growth factor

Fig. 5

Upregulated HB-EGF reverses the effect of miR-194 mimic in KGN cells growth and apoptosis. (A) The expression of HB-EGF in KGN cells post-transfection with HB-EGF-OE. (B) The expression of HB-EGF in KGN cells post transfection with miR-194 mimic or miR-194 mimic+HB-EGF-OE. (C-D) The apoptotic rate of KGN cells was determined using AO/EB and flow cytometry. 𝑛 = 3-6 for each group; *P < 0.05 vs. miR-NC mimic group

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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